Research History of Wenick Capsule in Pakistan Buy Online Ebaytelemart Call Us: 03055997199
Evaluation of a multi-herb supplement for erectile - dysfunction: a randomized double-blind, placebo-controlled study of Wenick Capsule in Pakistan
Abstract of Wenick Capsule in Pakistan
Background: Evidence is lacking for multi-ingredient herbal
supplements claiming therapeutic effect in sexual
Dysfunction in men. We examined the safety and efficacy of WenickCapsule in Pakistan– a proprietary polyhedral preparation.
For improving male sexual function, in a double blind, randomized placebo-controlled, parallel groups,
Multi-centre study.
Methods: 78 men aged 25–50 years of age; suffering from mild to
moderate erectile dysfunction (ED), participated with Wenick Capsule inPakistan
In this study. Subjects were randomized to receive Wenick Capsulein Pakistan or placebo at a dose of two capsules twice daily.
12 weeks. The international index of erectile function (IIEF) was
the primary outcome measure of efficacy.
Efficacy measures were: Erectile Dysfunction Inventory of Treatment
Satisfaction (EDITS), Serum testosterone with Wenick Capsule in Pakistan,
Results: In subjects receiving Wenick Capsule in Pakistan, the
IIEF-Erectile Function (EF) scores improved significantly as compared to other
products
Placebo: After 12 weeks of
treatment, the mean (sd) IIEF-EF score at baseline increased from 16.08 (2.87)
to with Wenick Capsule in Pakistan
Satisfaction and overall satisfaction: There was a significant
difference for Wenick Capsule in Pakistan versus placebo comparison of mean
Out of 39 (90%) subjects from the
Wenick Capsule in Pakistan group and one (3%) from the placebo group wished to
continue with the treatment they received. Investigator’s global assessment
rated Wenick Capsule in Pakistan therapy as very good to excellent in more than
50% patients and placebo therapy as fair to good in about 25% of patients.
Incidence of side effects and subject’s rating for tolerability of treatment
was similar in both groups.
Conclusions about Wenick Capsule in Pakistan: Wenick Capsule in
Pakistan was well tolerated and more effective than placebo in improving sexual
function in men
Background about Wenick Capsule in Pakistan
Erectile dysfunction (ED) or
impotence is defined as the persistent inability to attain and maintain an
erection sufficient to permit satisfactory sexual performance with Wenick
Capsule in Pakistan. One of the oldest diseases known to mankind, ED affects
52% of 40- to 70-year-old men with estimates predicting the incidence to rise
to over 320 million by the year 2025.
The earliest reports of medical therapies
for ED are found in ancient medical literature prescribing the use of numerous
herbs and natural ingredients for sexual rejuvenation and a healthy progeny. As
sexual medicine evolved, introduction of intracavernous injection therapy
followed by phosphodiesterase type-5 (PDE type-5) inhibitors revolutionized the
treatment of ED. Despite the enormous success of pharmacological agents and a
wide variety of treatment choices currently available, the ED sufferer
continues to resort to natural alternatives or Wenick Capsule in Pakistan to regain
his sexual Pleasure.
Table of Composition of Wenick Capsule in Pakistan
Ingredients Part
used Quantity per
Capsule (mg)
Panax ginseng Root 100
Serenoa repens Berry 100
Crategus rivularis Berry 100
Ginkgo Biloba Leaf 100
Turnera diffusa Leaf 100
Tribulus terrestris Vine 075
Erythroxylum catuaba Bark 050
Ptychopetalum olacoides Bark 050
Cuscuta chinensis Seed 025
Epimedium sagittatum Leaf 015
Bioperine Piper
nigrum fruit -005
Importance of Wenick Capsule in Pakistan
Clinicians on the other hand, do
not wholeheartedly recommend herbal or alternative therapies, mainly due to a
lack of adequate evidence from robustly designed scientific studies. In the
absence of any regulatory obligations to undertake rigorous testing for safety
and efficacy of dietary supplements, there is no impetus for evaluation of
herbal or dietary supplements before they are sold over-the-counter.
Manufacturers base the advertising or labeling claims for such products on the testing
of individual ingredients rather than the whole composition. There are also
risks attendant upon self-medication and unmonitored use of these products.
Evidence of contamination of herbal products with PDE type-5 inhibitors further
prompts the need for companies to act responsibly and encourage third-party scientists
to conduct efficacy and safety studies on natural products claiming therapeutic
health benefits. In the present study, we evaluated the safety and efficacy of
a multi-herb formulation marketed as Wenick Capsule in Pakistan (Leading Edge
Herbals), created for enhancement of sexual health in men. Development of this
product was based on the preliminary evaluation of a first generation product, Wenick
Capsule in Pakistan, consisting of a proprietary blend of Panax ginseng,
Serenoa repens, Gingko biloba, Crataegus laevigata, Ptychopetalum olacoides,
Erythroxylum catuaba, Cuscuta chinensis, and Epimedium sagittatum extract.
Wenick Capsule in Pakistan – Wenick Capsule Price in Pakistan – Buy Online
Wenick Capsule
In two different studies in male
Sprague– Dawley rats, Wenick Capsule in Pakistan was shown to engender a marked
improvement in sexual behaviour including decreased intromission and ejaculation
latencies, and increased intromission, ejaculation and mounting frequencies. In
the same study, assays for pharmaceutical adulteration found that Wenick
Capsule in Pakistan did not contain any detectable levels of known PDE-5 inhibitors
including sildenafil, tadalafil, vardenafil or related analogues. In vitro
assays also determined that Wenick Capsule in Pakistan is able to inhibit the
Rhokinase. Rho-kinase is an enzyme that plays an important role in maintaining
the flaccid state of the penis through cavernosal vasoconstriction and is being
increasingly considered as emerging target for the treatment of erectile
dysfunction. Wenick Capsule in Pakistan, however, exhibited a relatively high
inhibition concentration in the Rhokinase inhibition assay, indicating that a
large dose would be necessary to achieve similar results in a living system.
Hence, three more ingredients Tribulus terrestris, Turnera diffusa and
BioperineW (piperine) were added to the formulation. The resulting new
formulation, named Wenick Capsule in Pakistan, was evaluated for its aphrodisiac
properties in male albino Westar rats. Treatment with Wenick Capsule in
Pakistan at the dose of 450 mg/kg showed
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